6iiv

X-ray diffraction
3Å resolution

Crystal structure of the human thromboxane A2 receptor bound to daltroban

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-132346 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rubredoxin; Soluble cytochrome b562; Thromboxane A2 receptor Chain: A
Molecule details ›
Chain: A
Length: 484 amino acids
Theoretical weight: 53.24 KDa
Source organisms: Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P0ABE7 (Residues: 23-128; Coverage: 100%)
  • Canonical: P21731 (Residues: 10-228, 237-323; Coverage: 89%)
  • Canonical: P00268 (Residues: 1-54; Coverage: 100%)
Gene names: TBXA2R, cybC
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: C2221
Unit cell:
a: 81.53Å b: 152.17Å c: 125.22Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.209 0.237
Expression system: Spodoptera frugiperda