Function and Biology Details
Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 84-mer (preferred)
PDBe Complex ID:
PDB-CPX-140321 (preferred)
Entry contents:
77 distinct polypeptide molecules
6 distinct RNA molecules
6 distinct RNA molecules
Macromolecules (83 distinct):
Large ribosomal subunit protein uL2
Chain: 1D
Large ribosomal subunit protein uL3
Chain: 1E
Large ribosomal subunit protein uL4
Chain: 1F
Large ribosomal subunit protein uL18
Chain: 1G
Large ribosomal subunit protein eL6
Chain: 1H
Large ribosomal subunit protein uL30
Chain: 2A
Large ribosomal subunit protein eL8
Chain: 2B
Large ribosomal subunit protein uL6
Chain: 2C
Ribosomal protein uL16-like
Chain: 2D
Large ribosomal subunit protein uL5
Chain: 2E
Large ribosomal subunit protein eL13
Chain: 2F
Large ribosomal subunit protein eL14
Chain: 2G
Large ribosomal subunit protein eL15
Chain: 2H
Large ribosomal subunit protein uL13
Chain: 2I
Large ribosomal subunit protein uL22
Chain: 2J
Large ribosomal subunit protein eL18
Chain: 2K
Large ribosomal subunit protein eL19
Chain: 2L
Large ribosomal subunit protein eL20
Chain: 2M
Large ribosomal subunit protein eL21
Chain: 2N
Large ribosomal subunit protein eL22
Chain: 2O
Large ribosomal subunit protein uL14
Chain: 2P
Large ribosomal subunit protein eL24
Chain: 2Q
Large ribosomal subunit protein uL23
Chain: 2R
Large ribosomal subunit protein uL24
Chain: 2S
Large ribosomal subunit protein eL27
Chain: 2T
Large ribosomal subunit protein uL15
Chain: 2U
Large ribosomal subunit protein eL29
Chain: 2V
Large ribosomal subunit protein eL30
Chain: 2W
Large ribosomal subunit protein eL31
Chain: 2X
Large ribosomal subunit protein eL32
Chain: 2Y
Large ribosomal subunit protein eL33
Chain: 2Z
Large ribosomal subunit protein eL34
Chain: 2a
Large ribosomal subunit protein uL29
Chain: 2b
Large ribosomal subunit protein eL36
Chain: 2c
Large ribosomal subunit protein eL37
Chain: 2d
Large ribosomal subunit protein eL38
Chain: 2e
Large ribosomal subunit protein eL39
Chain: 2f
Ubiquitin-ribosomal protein eL40 fusion protein
Chain: 2g
Small ribosomal subunit protein eS32
Chain: 2h
Large ribosomal subunit protein eL42
Chain: 2i
Large ribosomal subunit protein eL43
Chain: 2j
Large ribosomal subunit protein eL28
Chain: 2k
Large ribosomal subunit protein uL1
Chain: 2l
Small ribosomal subunit protein uS2
Chain: 2n
Small ribosomal subunit protein eS1
Chain: 2o
Small ribosomal subunit protein uS3
Chain: 2p
Small ribosomal subunit protein eS4, X isoform
Chain: 2q
Small ribosomal subunit protein uS7
Chain: 2r
Small ribosomal subunit protein eS7
Chain: 2s
Small ribosomal subunit protein eS8
Chain: 2t
Small ribosomal subunit protein eS10
Chain: 2u
Small ribosomal subunit protein uS17
Chain: 2v
Small ribosomal subunit protein uS19
Chain: 2w
Small ribosomal subunit protein uS9
Chain: 2x
Small ribosomal subunit protein eS17
Chain: 2y
Small ribosomal subunit protein uS13
Chain: 2z
Small ribosomal subunit protein eS19
Chain: 20
Small ribosomal subunit protein uS10
Chain: 21
Small ribosomal subunit protein eS21
Chain: 3A
Small ribosomal subunit protein uS12
Chain: 3B
Small ribosomal subunit protein eS26
Chain: 3C
Small ribosomal subunit protein eS28
Chain: 3D
Small ribosomal subunit protein uS14
Chain: 3E
Small ribosomal subunit protein RACK1
Chain: 3F
Small ribosomal subunit protein uS5
Chain: 3G
Small ribosomal subunit protein eS6
Chain: 3H
Small ribosomal subunit protein uS4
Chain: 3I
Small ribosomal subunit protein eS12
Chain: 3J
Small ribosomal subunit protein uS15
Chain: 3K
Small ribosomal subunit protein uS11
Chain: 3L
Small ribosomal subunit protein uS8
Chain: 3M
Small ribosomal subunit protein eS24
Chain: 3N
Small ribosomal subunit protein eS25
Chain: 3O
Small ribosomal subunit protein eS27
Chain: 3P
Small ribosomal subunit protein eS30
Chain: 3Q
Ubiquitin-ribosomal protein eS31 fusion protein
Chain: 3R
nascent peptide
Chain: zx
28S ribosomal RNA
Chain: 1A
Molecule details ›
Chain: 1A
Length: 5070 nucleotides
Theoretical weight: 1640.18 KDa
Source organism: Homo sapiens
Sequence domains: Eukaryotic large subunit ribosomal RNA
Length: 5070 nucleotides
Theoretical weight: 1640.18 KDa
Source organism: Homo sapiens
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA
Chain: 1B
Molecule details ›
Chain: 1B
Length: 121 nucleotides
Theoretical weight: 39 KDa
Source organism: Homo sapiens
Sequence domains: 5S ribosomal RNA
Length: 121 nucleotides
Theoretical weight: 39 KDa
Source organism: Homo sapiens
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA
Chain: 1C
Molecule details ›
Chain: 1C
Length: 157 nucleotides
Theoretical weight: 50.45 KDa
Source organism: Homo sapiens
Sequence domains: 5.8S ribosomal RNA
Length: 157 nucleotides
Theoretical weight: 50.45 KDa
Source organism: Homo sapiens
Sequence domains: 5.8S ribosomal RNA
18S Ribosomal RNA
Chain: 2m
Molecule details ›
Chain: 2m
Length: 1869 nucleotides
Theoretical weight: 602.75 KDa
Source organism: Homo sapiens
Sequence domains: Eukaryotic small subunit ribosomal RNA
Length: 1869 nucleotides
Theoretical weight: 602.75 KDa
Source organism: Homo sapiens
Sequence domains: Eukaryotic small subunit ribosomal RNA
Messenger RNA
Chain: zv
P-site tRNA
Chains: zu, zy
Molecule details ›
Chains: zu, zy
Length: 75 nucleotides
Theoretical weight: 24.19 KDa
Source organism: Homo sapiens
Sequence domains: tRNA
Length: 75 nucleotides
Theoretical weight: 24.19 KDa
Source organism: Homo sapiens
Sequence domains: tRNA