› 6iu1

X-ray diffraction
2.89Å resolution

Peroxiredoxin from Pyrococcus horikoshii 0Cys mutant)

Released:
DOI: 10.2210/pdb6iu1/pdb
PDB entry 6iu1 coloured by chain, front view.
PDB entry 6iu1 coloured by chain, side view.
PDB entry 6iu1 coloured by chain, top view.
Source organism: Pyrococcus horikoshii OT3
Primary publication:
Distinct molecular assembly of homologous peroxiredoxins from Pyrococcus horikoshii and Thermococcus kodakaraensis.
Himiyama T, Oshima M, Uegaki K, Nakamura T
J Biochem 166 89-95 (2019)
PMID: 30796432

Function and Biology Details

Reaction catalysed: 
Thioredoxin + ROOH = thioredoxin disulfide + H(2)O + ROH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129788 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxiredoxin Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Length: 216 amino acids
Theoretical weight: 24.74 KDa
Source organism: Pyrococcus horikoshii OT3
Expression system: Escherichia coli
UniProt:
  • Canonical: O58966 (Residues: 1-216; Coverage: 100%)
Gene names: PH1217, ahpC
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL38B1
Spacegroup: P21
Unit cell:
a: 125.877Å b: 95.284Å c: 231.796Å
α: 90° β: 104.43° γ: 90°
R-values:
R R work R free
0.234 0.231 0.296
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Disassembly of the ring-type decameric structure of peroxiredoxin from Aeropyrum pernix K1 by amino acid mutation.
Himiyama et al. (2020)