› 6j1u

X-ray diffraction
2.8Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147424 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 498 amino acids
Theoretical weight: 56.45 KDa
Source organism: Influenza A virus (A/Wilson-Smith/1933(H1N1))
Expression system: Escherichia coli
UniProt:
  • Canonical: P15682 (Residues: 1-498; Coverage: 100%)
Gene name: NP
Sequence domains: Influenza virus nucleoprotein

Ligands and Environments

1 bound ligand:
Ligand B7O 3 x B7O
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: C2221
Unit cell:
a: 119.592Å b: 126.747Å c: 194.425Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.191 0.26
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Antiviral Drugs in Influenza.
Świerczyńska et al. (2022)
1 more

4 mentions without citation

Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle.
Yang et al. (2021)
3 more