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Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom

Source organism: Saccharomyces cerevisiae S288C
Biochemical function: protein binding
Biological process: RNA splicing
Cellular component: spliceosomal complex

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EC 2.3.2.27: RING-type E3 ubiquitin transferase

Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Systematic name:
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein]-L-lysine ubiquitin transferase (isopeptide bond-forming; RING-type)
Alternative Name(s):
  • RING E3 ligase
  • Ubiquitin transferase RING E3

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF01423
Domain description: LSM domain
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D2
  2. Small nuclear ribonucleoprotein F
  3. Small nuclear ribonucleoprotein E
  4. Small nuclear ribonucleoprotein G
  5. Small nuclear ribonucleoprotein-associated protein B
  6. Small nuclear ribonucleoprotein Sm D3
  7. Small nuclear ribonucleoprotein Sm D1
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein E. Showing 1 copy in chain X [auth u].
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein Sm D1. Showing 1 copy in chain Y [auth m].
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein G. Showing 1 copy in chain IA [auth x].
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein F. Showing 1 copy in chain HA [auth w].
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein Sm D2. Showing 1 copy in chain DA [auth e].
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein-associated protein B. Showing 1 copy in chain CA [auth k].
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF01423 (LSM domain ) in Small nuclear ribonucleoprotein Sm D3. Showing 1 copy in chain FA [auth l].

PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Pre-mRNA-splicing factor PRP46
  2. Pre-mRNA-processing factor 17
The deposited structure of PDB entry 6j6h contains 5 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Pre-mRNA-splicing factor PRP46. Showing 5 copies in chain D [auth O].
The deposited structure of PDB entry 6j6h contains 4 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Pre-mRNA-processing factor 17. Showing 4 copies in chain N [auth n] (this domain is out of the observed residue ranges!).

PF08606
Domain description: Prp19/Pso4-like
Occurring in:
  1. Pre-mRNA-processing factor 19
The deposited structure of PDB entry 6j6h contains 4 copies of Pfam domain PF08606 (Prp19/Pso4-like) in Pre-mRNA-processing factor 19. Showing 1 copy in chain NA [auth q].

PF05843
Domain description: Suppressor of forked protein (Suf)
Occurring in:
  1. Pre-mRNA-splicing factor CLF1
  2. Pre-mRNA-splicing factor SYF1
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF05843 (Suppressor of forked protein (Suf)) in Pre-mRNA-splicing factor CLF1. Showing 1 copy in chain L [auth d].
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF05843 (Suppressor of forked protein (Suf)) in Pre-mRNA-splicing factor SYF1. Showing 1 copy in chain T [auth v].

PF00249
Domain description: Myb-like DNA-binding domain
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
The deposited structure of PDB entry 6j6h contains 2 copies of Pfam domain PF00249 (Myb-like DNA-binding domain) in Pre-mRNA-splicing factor CEF1. Showing 2 copies in chain K [auth c].

PF11831
Domain description: pre-mRNA splicing factor component
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF11831 (pre-mRNA splicing factor component) in Pre-mRNA-splicing factor CEF1. Showing 1 copy in chain K [auth c].

PF14580
Domain description: Leucine-rich repeat
Occurring in:
  1. U2 small nuclear ribonucleoprotein A'
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF14580 (Leucine-rich repeat) in U2 small nuclear ribonucleoprotein A'. Showing 1 copy in chain V [auth b].

PF13893
Domain description: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Occurring in:
  1. U2 small nuclear ribonucleoprotein B''
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF13893 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) in U2 small nuclear ribonucleoprotein B''. Showing 1 copy in chain U [auth a].

PF02847
Domain description: MA3 domain
Occurring in:
  1. Pre-mRNA-splicing factor CWC22
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF02847 (MA3 domain) in Pre-mRNA-splicing factor CWC22. Showing 1 copy in chain J [auth Z].

PF01125
Domain description: Pre-mRNA-splicing factor BUD31
Occurring in:
  1. Pre-mRNA-splicing factor BUD31
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF01125 (Pre-mRNA-splicing factor BUD31) in Pre-mRNA-splicing factor BUD31. Showing 1 copy in chain I [auth T].

PF04889
Domain description: Cwf15/Cwc15 cell cycle control protein
Occurring in:
  1. Pre-mRNA-splicing factor CWC15
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF04889 (Cwf15/Cwc15 cell cycle control protein) in Pre-mRNA-splicing factor CWC15. Showing 1 copy in chain H [auth S].

PF00076
Domain description: RNA recognition motif
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF00076 (RNA recognition motif) in Pre-mRNA-splicing factor CWC2. Showing 1 copy in chain G [auth R].

PF16131
Domain description: Torus domain
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF16131 (Torus domain) in Pre-mRNA-splicing factor CWC2. Showing 1 copy in chain G [auth R].

PF21369
Domain description: STL11, N-terminal
Occurring in:
  1. Pre-mRNA-splicing factor SLT11
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF21369 (STL11, N-terminal) in Pre-mRNA-splicing factor SLT11. Showing 1 copy in chain F [auth Q].

PF02731
Domain description: SKIP/SNW domain
Occurring in:
  1. Pre-mRNA-processing protein 45
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF02731 (SKIP/SNW domain) in Pre-mRNA-processing protein 45. Showing 1 copy in chain E [auth P].

PF08312
Domain description: cwf21 domain
Occurring in:
  1. Pre-mRNA-splicing factor CWC21
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF08312 (cwf21 domain) in Pre-mRNA-splicing factor CWC21. Showing 1 copy in chain C [auth J] (this domain is out of the observed residue ranges!).

PF08231
Domain description: SYF2 splicing factor
Occurring in:
  1. Pre-mRNA-splicing factor SYF2
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF08231 (SYF2 splicing factor) in Pre-mRNA-splicing factor SYF2. Showing 1 copy in chain M [auth I].

PF06246
Domain description: Isy1-like splicing family
Occurring in:
  1. Pre-mRNA-splicing factor ISY1
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF06246 (Isy1-like splicing family) in Pre-mRNA-splicing factor ISY1. Showing 1 copy in chain O [auth H].

PF00679
Domain description: Elongation factor G C-terminus
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF00679 (Elongation factor G C-terminus) in Pre-mRNA-splicing factor SNU114. Showing 1 copy in chain B [auth C].

PF03764
Domain description: Elongation factor G, domain IV
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF03764 (Elongation factor G, domain IV) in Pre-mRNA-splicing factor SNU114. Showing 1 copy in chain B [auth C].

PF00009
Domain description: Elongation factor Tu GTP binding domain
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF00009 (Elongation factor Tu GTP binding domain) in Pre-mRNA-splicing factor SNU114. Showing 1 copy in chain B [auth C].

PF16004
Domain description: 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF16004 (116 kDa U5 small nuclear ribonucleoprotein component N-terminus) in Pre-mRNA-splicing factor SNU114. Showing 1 copy in chain B [auth C].

PF08084
Domain description: PROCT (NUC072) domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF08084 (PROCT (NUC072) domain) in Pre-mRNA-splicing factor 8. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF12134
Domain description: PRP8 domain IV core
Occurring in:
  1. Pre-mRNA-splicing factor 8
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF12134 (PRP8 domain IV core) in Pre-mRNA-splicing factor 8. Showing 1 copy in chain A.

PF10596
Domain description: U6-snRNA interacting domain of PrP8
Occurring in:
  1. Pre-mRNA-splicing factor 8
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF10596 (U6-snRNA interacting domain of PrP8) in Pre-mRNA-splicing factor 8. Showing 1 copy in chain A.

PF10597
Domain description: U5-snRNA binding site 2 of PrP8
Occurring in:
  1. Pre-mRNA-splicing factor 8
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF10597 (U5-snRNA binding site 2 of PrP8) in Pre-mRNA-splicing factor 8. Showing 1 copy in chain A.

PF10598
Domain description: RNA recognition motif of the spliceosomal PrP8
Occurring in:
  1. Pre-mRNA-splicing factor 8
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF10598 (RNA recognition motif of the spliceosomal PrP8) in Pre-mRNA-splicing factor 8. Showing 1 copy in chain A.

PF08083
Domain description: PROCN (NUC071) domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF08083 (PROCN (NUC071) domain) in Pre-mRNA-splicing factor 8. Showing 1 copy in chain A.

PF08082
Domain description: PRO8NT (NUC069), PrP8 N-terminal domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
The deposited structure of PDB entry 6j6h contains 1 copy of Pfam domain PF08082 (PRO8NT (NUC069), PrP8 N-terminal domain) in Pre-mRNA-splicing factor 8. Showing 1 copy in chain A.

Rfam RNA families (Rfam)
RF00020
Domain description: U5 spliceosomal RNA
Occurring in:
  1. U5 snRNA
The deposited structure of PDB entry 6j6h contains 1 copy of Rfam domain RF00020 (U5 spliceosomal RNA) in U5 snRNA. Showing 1 copy in chain Q [auth D].

RF00026
Domain description: U6 spliceosomal RNA
Occurring in:
  1. U6 snRNA
The deposited structure of PDB entry 6j6h contains 1 copy of Rfam domain RF00026 (U6 spliceosomal RNA) in U6 snRNA. Showing 1 copy in chain R [auth E].

RF00004
Domain description: U2 spliceosomal RNA
Occurring in:
  1. U2 snRNA
The deposited structure of PDB entry 6j6h contains 1 copy of Rfam domain RF00004 (U2 spliceosomal RNA) in U2 snRNA. Showing 1 copy in chain S [auth L].

InterPro InterPro annotations
IPR001680
Domain description: WD40 repeat
Occurring in:
  1. Pre-mRNA-splicing factor PRP46
  2. Pre-mRNA-processing factor 17
IPR001163
Domain description: Sm domain, eukaryotic/archaea-type
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D2
  2. Small nuclear ribonucleoprotein F
  3. Small nuclear ribonucleoprotein E
  4. Small nuclear ribonucleoprotein G
  5. Small nuclear ribonucleoprotein-associated protein B
  6. Small nuclear ribonucleoprotein Sm D3
  7. Small nuclear ribonucleoprotein Sm D1
IPR003107
Domain description: HAT (Half-A-TPR) repeat
Occurring in:
  1. Pre-mRNA-splicing factor CLF1
  2. Pre-mRNA-splicing factor SYF1
IPR047575
Domain description: Sm domain
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D2
  2. Small nuclear ribonucleoprotein F
  3. Small nuclear ribonucleoprotein E
  4. Small nuclear ribonucleoprotein G
  5. Small nuclear ribonucleoprotein-associated protein B
  6. Small nuclear ribonucleoprotein Sm D3
  7. Small nuclear ribonucleoprotein Sm D1
IPR010920
Domain description: LSM domain superfamily
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D2
  2. Small nuclear ribonucleoprotein F
  3. Small nuclear ribonucleoprotein E
  4. Small nuclear ribonucleoprotein G
  5. Small nuclear ribonucleoprotein-associated protein B
  6. Small nuclear ribonucleoprotein Sm D3
  7. Small nuclear ribonucleoprotein Sm D1
IPR011990
Domain description: Tetratricopeptide-like helical domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor CLF1
  2. Pre-mRNA-splicing factor SYF1
IPR003613
Domain description: U-box domain
Occurring in:
  1. Pre-mRNA-processing factor 19
IPR001748
Domain description: Pre-mRNA-splicing factor BUD31
Occurring in:
  1. Pre-mRNA-splicing factor BUD31
IPR020472
Domain description: G-protein beta WD-40 repeat
Occurring in:
  1. Pre-mRNA-splicing factor PRP46
  2. Pre-mRNA-processing factor 17
IPR015943
Domain description: WD40/YVTN repeat-like-containing domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor PRP46
  2. Pre-mRNA-processing factor 17
  3. Pre-mRNA-processing factor 19
IPR000795
Domain description: Translational (tr)-type GTP-binding domain
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR001005
Domain description: SANT/Myb domain
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
IPR038959
Domain description: Pre-mRNA-processing factor 19
Occurring in:
  1. Pre-mRNA-processing factor 19
IPR011047
Domain description: Quinoprotein alcohol dehydrogenase-like superfamily
Occurring in:
  1. Pre-mRNA-processing factor 19
IPR013915
Domain description: Pre-mRNA-splicing factor 19, coiled-coil region
Occurring in:
  1. Pre-mRNA-processing factor 19
IPR013083
Domain description: Zinc finger, RING/FYVE/PHD-type
Occurring in:
  1. Pre-mRNA-processing factor 19
IPR027141
Domain description: Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D3
  2. Small nuclear ribonucleoprotein Sm D1
IPR027078
Domain description: Small nuclear ribonucleoprotein E
Occurring in:
  1. Small nuclear ribonucleoprotein E
IPR027248
Domain description: Small nuclear ribonucleoprotein Sm D2
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D2
IPR000504
Domain description: RNA recognition motif domain
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
  2. U2 small nuclear ribonucleoprotein B''
IPR034102
Domain description: Small nuclear ribonucleoprotein D1
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D1
IPR034099
Domain description: Small nuclear ribonucleoprotein Sm D3
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D3
IPR044641
Domain description: Sm-like protein Lsm7/SmG
Occurring in:
  1. Small nuclear ribonucleoprotein G
IPR034098
Domain description: Small nuclear ribonucleoprotein G
Occurring in:
  1. Small nuclear ribonucleoprotein G
IPR034100
Domain description: Small nuclear ribonucleoprotein F
Occurring in:
  1. Small nuclear ribonucleoprotein F
IPR016487
Domain description: Sm-like protein Lsm6/SmF
Occurring in:
  1. Small nuclear ribonucleoprotein F
IPR045075
Domain description: Pre-mRNA-splicing factor Syf1-like
Occurring in:
  1. Pre-mRNA-splicing factor CLF1
  2. Pre-mRNA-splicing factor SYF1
IPR017930
Domain description: Myb domain
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
IPR003891
Domain description: Initiation factor eIF-4 gamma, MA3
Occurring in:
  1. Pre-mRNA-splicing factor CWC22
IPR018230
Domain description: BUD31/G10-related, conserved site
Occurring in:
  1. Pre-mRNA-splicing factor BUD31
IPR006973
Domain description: Pre-mRNA-splicing factor Cwf15/Cwc15
Occurring in:
  1. Pre-mRNA-splicing factor CWC15
IPR035979
Domain description: RNA-binding domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
  2. U2 small nuclear ribonucleoprotein B''
IPR012677
Domain description: Nucleotide-binding alpha-beta plait domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
  2. U2 small nuclear ribonucleoprotein B''
IPR039171
Domain description: Pre-mRNA-splicing factor Cwc2/Slt11
Occurring in:
  1. Pre-mRNA-splicing factor SLT11
  2. Pre-mRNA-splicing factor CWC2
IPR019775
Domain description: WD40 repeat, conserved site
Occurring in:
  1. Pre-mRNA-splicing factor PRP46
IPR036322
Domain description: WD40-repeat-containing domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor PRP46
  2. Pre-mRNA-processing factor 17
IPR013170
Domain description: mRNA splicing factor Cwf21 domain
Occurring in:
  1. Pre-mRNA-splicing factor CWC21
IPR009360
Domain description: Pre-mRNA-splicing factor Isy1
Occurring in:
  1. Pre-mRNA-splicing factor ISY1
IPR000640
Domain description: Elongation factor EFG, domain V-like
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR005517
Domain description: Translation elongation factor EFG/EF2, domain IV
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR035647
Domain description: EF-G domain III/V-like
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR021983
Domain description: PRP8 domain IV core
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR012337
Domain description: Ribonuclease H-like superfamily
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR032847
Domain description: Pre-mRNA-processing factor 17
Occurring in:
  1. Pre-mRNA-processing factor 17
IPR021786
Domain description: Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
IPR047240
Domain description: Pre-mRNA splicing factor component CDC5L/Cef1, second SANT/myb-like domain
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
IPR009057
Domain description: Homedomain-like superfamily
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
IPR047242
Domain description: Pre-mRNA splicing factor component CDC5L/Cef1
Occurring in:
  1. Pre-mRNA-splicing factor CEF1
IPR003603
Domain description: U2A'/phosphoprotein 32 family A, C-terminal
Occurring in:
  1. U2 small nuclear ribonucleoprotein A'
IPR001611
Domain description: Leucine-rich repeat
Occurring in:
  1. U2 small nuclear ribonucleoprotein A'
IPR032675
Domain description: Leucine-rich repeat domain superfamily
Occurring in:
  1. U2 small nuclear ribonucleoprotein A'
IPR044640
Domain description: U2 small nuclear ribonucleoprotein A'
Occurring in:
  1. U2 small nuclear ribonucleoprotein A'
IPR003890
Domain description: MIF4G-like, type 3
Occurring in:
  1. Pre-mRNA-splicing factor CWC22
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Pre-mRNA-splicing factor CWC22
IPR034181
Domain description: Pre-mRNA-splicing factor Cwc2, RNA recognition motif
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
IPR000571
Domain description: Zinc finger, CCCH-type
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
IPR032297
Domain description: Torus domain
Occurring in:
  1. Pre-mRNA-splicing factor CWC2
IPR034356
Domain description: Slt11, RNA recognition motif
Occurring in:
  1. Pre-mRNA-splicing factor SLT11
IPR017862
Domain description: SKI-interacting protein, SKIP
Occurring in:
  1. Pre-mRNA-processing protein 45
IPR004015
Domain description: SKI-interacting protein SKIP, SNW domain
Occurring in:
  1. Pre-mRNA-processing protein 45
IPR045241
Domain description: WD repeat Prp46/PLRG1-like
Occurring in:
  1. Pre-mRNA-splicing factor PRP46
IPR013260
Domain description: mRNA splicing factor SYF2
Occurring in:
  1. Pre-mRNA-splicing factor SYF2
IPR029012
Domain description: Helix hairpin bin domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor ISY1
IPR037200
Domain description: Pre-mRNA-splicing factor Isy1 superfamily
Occurring in:
  1. Pre-mRNA-splicing factor ISY1
IPR035655
Domain description: 116kDa U5 small nuclear ribonucleoprotein component, C-terminal
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR014721
Domain description: Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR020568
Domain description: Ribosomal protein uS5 domain 2-type superfamily
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR004161
Domain description: Translation elongation factor EFTu-like, domain 2
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR009000
Domain description: Translation protein, beta-barrel domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR044121
Domain description: Snu114, GTP-binding domain
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR031950
Domain description: 116kDa U5 small nuclear ribonucleoprotein component, N-terminal
Occurring in:
  1. Pre-mRNA-splicing factor SNU114
IPR012984
Domain description: PROCT domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR037518
Domain description: MPN domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR000555
Domain description: JAB1/MPN/MOV34 metalloenzyme domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR043173
Domain description: Prp8 RNase domain IV, fingers region
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR043172
Domain description: Prp8 RNase domain IV, palm region
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR019580
Domain description: Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR019581
Domain description: Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR042516
Domain description: Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR019582
Domain description: RNA recognition motif, spliceosomal PrP8
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR012592
Domain description: PROCN domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR012591
Domain description: PRO8NT domain
Occurring in:
  1. Pre-mRNA-splicing factor 8
IPR027652
Domain description: Pre-mRNA-processing-splicing factor 8
Occurring in:
  1. Pre-mRNA-splicing factor 8

Structure domains

CATH CATH domains
2.30.30.100
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 type barrels.
Occurring in:
  1. Small nuclear ribonucleoprotein Sm D2
  2. Small nuclear ribonucleoprotein F
  3. Small nuclear ribonucleoprotein E
  4. Small nuclear ribonucleoprotein G
  5. Small nuclear ribonucleoprotein Sm D3
The deposited structure of PDB entry 6j6h contains 2 copies of CATH domain 2.30.30.100 (SH3 type barrels.) in Small nuclear ribonucleoprotein E. Showing 1 copy in chain GA [auth i].
The deposited structure of PDB entry 6j6h contains 2 copies of CATH domain 2.30.30.100 (SH3 type barrels.) in Small nuclear ribonucleoprotein G. Showing 1 copy in chain Z [auth j].
The deposited structure of PDB entry 6j6h contains 2 copies of CATH domain 2.30.30.100 (SH3 type barrels.) in Small nuclear ribonucleoprotein F. Showing 1 copy in chain AA [auth h].
The deposited structure of PDB entry 6j6h contains 2 copies of CATH domain 2.30.30.100 (SH3 type barrels.) in Small nuclear ribonucleoprotein Sm D2. Showing 1 copy in chain DA [auth e].
The deposited structure of PDB entry 6j6h contains 2 copies of CATH domain 2.30.30.100 (SH3 type barrels.) in Small nuclear ribonucleoprotein Sm D3. Showing 1 copy in chain FA [auth l].
3.30.70.330
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Alpha-Beta Plaits
Occurring in:
  1. U2 small nuclear ribonucleoprotein B''
The deposited structure of PDB entry 6j6h contains 1 copy of CATH domain 3.30.70.330 (Alpha-Beta Plaits) in U2 small nuclear ribonucleoprotein B''. Showing 1 copy in chain U [auth a].

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