Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero 300-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209376 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
Capsid protein VP1
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 30.82 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
UniProt:
Length: 278 amino acids
Theoretical weight: 30.82 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
UniProt:
- Canonical:
P08617 (Residues: 492-769; Coverage: 13%)
Capsid protein VP2
Molecule details ›
Chain: B
Length: 222 amino acids
Theoretical weight: 24.9 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
UniProt:
Length: 222 amino acids
Theoretical weight: 24.9 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
UniProt:
- Canonical: P08617 (Residues: 24-245; Coverage: 10%)
Capsid protein VP3
Molecule details ›
Chain: C
Length: 246 amino acids
Theoretical weight: 27.84 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
UniProt:
Length: 246 amino acids
Theoretical weight: 27.84 KDa
Source organism: Human hepatitis A virus Hu/Australia/HM175/1976
UniProt:
- Canonical: P08617 (Residues: 246-491; Coverage: 11%)
