› 6jkv

X-ray diffraction
2.1Å resolution

PppA, a key regulatory component of T6SS in Pseudomonas aeruginosa

Released:
DOI: 10.2210/pdb6jkv/pdb
PDB entry 6jkv coloured by chain, front view.
PDB entry 6jkv coloured by chain, side view.
PDB entry 6jkv coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
Crystal structure of PppA from Pseudomonas aeruginosa, a key regulatory component of type VI secretion systems.
Wu Y, Gong J, Liu S, Li D, Wu Y, Zhang X, Ren Y, Xu S, Sun J, Wang T, Lin Q, Liu L
Biochem Biophys Res Commun 516 196-201 (2019)
PMID: 31208722

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191500 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PPM-type phosphatase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 262 amino acids
Theoretical weight: 28.11 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9I757 (Residues: 1-242; Coverage: 100%)
Gene names: PA0075, pppA
Sequence domains: Protein phosphatase 2C

Ligands and Environments

1 bound ligand:
Ligand MN 4 x MN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21
Unit cell:
a: 50.541Å b: 80.253Å c: 59.084Å
α: 90° β: 111.81° γ: 90°
R-values:
R R work R free
0.235 0.233 0.283
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Dephosphocholination by Legionella effector Lem3 functions through remodelling of the switch II region of Rab1b.
Kaspers et al. (2023)