› 6k22

X-ray diffraction
2.75Å resolution

Crystal structure of Ca-bound human Annexin A5 in low salt condition

Released:
DOI: 10.2210/pdb6k22/pdb
Model geometry
Fit model/data
PDB entry 6k22 coloured by chain, front view.
PDB entry 6k22 coloured by chain, side view.
PDB entry 6k22 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution structures of annexin A5 in a two-dimensional array.
Hong S, Na S, Kim OH, Jeong S, Oh BC, Ha NC
J Struct Biol 209 107401 (2020)
PMID: 31605770

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140372 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A5 Chain: A
Molecule details ›
Chain: A
Length: 331 amino acids
Theoretical weight: 37.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P08758 (Residues: 2-320; Coverage: 100%)
Gene names: ANX5, ANXA5, ENX2, PP4
Sequence domains: Annexin

Ligands and Environments

1 bound ligand:
Ligand CA 3 x CA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P6322
Unit cell:
a: 92.795Å b: 92.795Å c: 134.055Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.253 0.25 0.306
Expression system: Escherichia coli BL21

Quick links

Citations

2 citation in other articles

Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment.
Lillebostad et al. (2020)
1 more