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The crystal structure of cytidine deaminase from Klebsiella pneumoniae

Source organism: Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Biochemical function: metal ion binding
Biological process: carbohydrate derivative metabolic process
Cellular component: cytosol

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EC 3.5.4.5: Cytidine deaminase

Reaction catalysed:
2'-deoxycytidine + H(2)O = 2'-deoxyuridine + NH(3)
Systematic name:
Cytidine/2'-deoxycytidine aminohydrolase
Alternative Name(s):
  • (Deoxy)cytidine deaminase
  • CDA (gene name)
  • Cdd (gene name)
  • Cytidine aminohydrolase
  • Cytosine nucleoside deaminase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF08211
Domain description: Cytidine and deoxycytidylate deaminase zinc-binding region
Occurring in:
  1. Cytidine deaminase
The deposited structure of PDB entry 6k63 contains 4 copies of Pfam domain PF08211 (Cytidine and deoxycytidylate deaminase zinc-binding region ) in Cytidine deaminase. Showing 1 copy in chain A.

PF00383
Domain description: Cytidine and deoxycytidylate deaminase zinc-binding region
Occurring in:
  1. Cytidine deaminase
The deposited structure of PDB entry 6k63 contains 4 copies of Pfam domain PF00383 (Cytidine and deoxycytidylate deaminase zinc-binding region) in Cytidine deaminase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002125
Domain description: Cytidine and deoxycytidylate deaminase domain
Occurring in:
  1. Cytidine deaminase
IPR016193
Domain description: Cytidine deaminase-like
Occurring in:
  1. Cytidine deaminase
IPR013171
Domain description: Cytidine/deoxycytidylate deaminase, zinc-binding domain
Occurring in:
  1. Cytidine deaminase
IPR016192
Domain description: APOBEC/CMP deaminase, zinc-binding
Occurring in:
  1. Cytidine deaminase
IPR006263
Domain description: Cytidine deaminase, homodimeric
Occurring in:
  1. Cytidine deaminase
IPR020797
Domain description: Cytidine deaminase, bacteria
Occurring in:
  1. Cytidine deaminase

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