› 6k8v

X-ray diffraction
2.2Å resolution

Crystal structure of N-domain of baterial malonyl-CoA reductase

Released:
DOI: 10.2210/pdb6k8v/pdb
PDB entry 6k8v coloured by chain, front view.
PDB entry 6k8v coloured by chain, side view.
PDB entry 6k8v coloured by chain, top view.
Source organism: Erythrobacter dokdonensis DSW-74
Primary publication:
Structural insight into bi-functional malonyl-CoA reductase.
Son HF, Kim S, Seo H, Hong J, Lee D, Jin KS, Park S, Kim KJ
Environ Microbiol 22 752-765 (2020)
PMID: 31814251

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103209 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD-dependent epimerase/dehydratase:Short-chain dehydrogenase/reductase SDR Chains: A, B
Molecule details ›
Chains: A, B
Length: 575 amino acids
Theoretical weight: 61.27 KDa
Source organism: Erythrobacter dokdonensis DSW-74
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0A1A7BFR5 (Residues: 1-567; Coverage: 46%)
Gene name: I603_0811
Sequence domains: short chain dehydrogenase

Ligands and Environments

2 bound ligands:
Ligand SO4 13 x SO4
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P212121
Unit cell:
a: 85.637Å b: 109.072Å c: 129.422Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.198 0.258
Expression system: Escherichia coli BL21(DE3)

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Citations

1 citations in other articles

Synthetic anaplerotic modules for the direct synthesis of complex molecules from CO2.
Diehl et al. (2023)

2 mentions without citation

Increased CO2 fixation enables high carbon-yield production of 3-hydroxypropionic acid in yeast.
Qin et al. (2024)
1 more