› 6kjy

X-ray diffraction
1.5Å resolution

Galectin-13 variant C136S/C138S

Released:
DOI: 10.2210/pdb6kjy/pdb
PDB entry 6kjy coloured by chain, front view.
PDB entry 6kjy coloured by chain, side view.
PDB entry 6kjy coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Galectin-13/placental protein 13: redox-active disulfides as switches for regulating structure, function and cellular distribution.
Yang T, Yao Y, Wang X, Li Y, Si Y, Li X, Ayala GJ, Wang Y, Mayo KH, Tai G, Zhou Y, Su J
Glycobiology 30 120-129 (2020)
PMID: 31584064

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-577444 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galactoside-binding soluble lectin 13 Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 16.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UHV8 (Residues: 1-139; Coverage: 100%)
Gene names: LGALS13, PLAC8
Sequence domains: Galactoside-binding lectin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P43212
Unit cell:
a: 53.51Å b: 53.51Å c: 113.766Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.186 0.205
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The Emerging Role of Galectins and O-GlcNAc Homeostasis in Processes of Cellular Differentiation.
Tazhitdinova et al. (2020)
2 more