› 6klm

Solution NMR

NMR solution structure of Roseltide rT7

Released:
DOI: 10.2210/pdb6klm/pdb
PDB entry 6klm coloured by chain, ensemble of 17 models, front view.
PDB entry 6klm coloured by chain, ensemble of 17 models, side view.
PDB entry 6klm coloured by chain, ensemble of 17 models, top view.
Source organism: Hibiscus sabdariffa
Primary publication:
Roseltide rT7 is a disulfide-rich, anionic, and cell-penetrating peptide that inhibits proteasomal degradation.
Kam A, Loo S, Fan JS, Sze SK, Yang D, Tam JP
J Biol Chem 294 19604-19615 (2019)
PMID: 31727740

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-288678 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Roseltide rT7 Chain: A
Molecule details ›
Chain: A
Length: 34 amino acids
Theoretical weight: 3.71 KDa
Source organism: Hibiscus sabdariffa
UniProt:
  • Canonical: A0A5S8WF60 (Residues: 1-34; Coverage: 100%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 41%
Refinement method: simulated annealing

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Citations

4 review citations

Thiol-Mediated Uptake.
Laurent et al. (2021)
3 more

2 mentions without citation

Roseltide rT7 is a disulfide-rich, anionic, and cell-penetrating peptide that inhibits proteasomal degradation.
Kam et al. (2019)
1 more