6kmh

X-ray diffraction
2.4Å resolution

The crystal structure of CASK/Mint1 complex

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-127209 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peripheral plasma membrane protein CASK Chains: A, B
Molecule details ›
Chains: A, B
Length: 325 amino acids
Theoretical weight: 36.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14936 (Residues: 1-319; Coverage: 34%)
Gene names: CASK, LIN2
Sequence domains: Protein kinase domain
Amyloid-beta A4 precursor protein-binding family A member 1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 66 amino acids
Theoretical weight: 7.73 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O35430 (Residues: 338-397; Coverage: 7%)
Gene names: Apba1, Mint1, X11

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P212121
Unit cell:
a: 93.978Å b: 96.321Å c: 97.56Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.188 0.224
Expression system: Escherichia coli