6kzp

Electron Microscopy
3.1Å resolution

calcium channel-ligand

Released:
Source organism: Homo sapiens
Primary publication:
Cryo-EM structures of apo and antagonist-bound human Cav3.1.
Nature 576 492-497 (2019)
PMID: 31766050
Related structures: EMD-0792

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-128938 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-dependent T-type calcium channel subunit alpha-1G Chain: A
Molecule details ›
Chain: A
Length: 2146 amino acids
Theoretical weight: 238.87 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: O43497 (Residues: 2-2377; Coverage: 89%)
  • Best match: O43497-9 (Residues: 2-2261)
Gene names: CACNA1G, KIAA1123
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.1Å
Relevant EMDB volumes: EMD-0792
Expression system: Homo sapiens