› 6l1i

X-ray diffraction
1.85Å resolution

Crystal Structure Of of PHF20L1 Tudor1 Y24W/Y29W mutant

Released:
DOI: 10.2210/pdb6l1i/pdb
PDB entry 6l1i coloured by chain, front view.
PDB entry 6l1i coloured by chain, side view.
PDB entry 6l1i coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Conformational Selection in Ligand Recognition by the First Tudor Domain of PHF20L1.
Lv M, Gao J, Li M, Ma R, Li F, Liu Y, Liu M, Zhang J, Yao X, Wu J, Shi Y, Tang Y, Pan Y, Zhang Z, Ruan K
J Phys Chem Lett 11 7932-7938 (2020)
PMID: 32885980

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108756 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PHD finger protein 20-like protein 1 Chain: B
Molecule details ›
Chain: B
Length: 70 amino acids
Theoretical weight: 8.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: A8MW92 (Residues: 5-70; Coverage: 7%)
Gene names: CGI-72, PHF20L1

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P65
Unit cell:
a: 63.124Å b: 63.124Å c: 26.98Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.16 0.208
Expression system: Escherichia coli

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Citations

2 citation in other articles

Inhibitors against Two PDZ Domains of MDA-9 Suppressed Migration of Breast Cancer Cells.
Tang et al. (2023)
1 more