› 6l2b

X-ray diffraction
2.65Å resolution

Crystal structure of cyclophilin mutant I164M from Leishmania donovani at 2.65 angstrom resolution

Released:
DOI: 10.2210/pdb6l2b/pdb
PDB entry 6l2b coloured by chain, front view.
PDB entry 6l2b coloured by chain, side view.
PDB entry 6l2b coloured by chain, top view.
Source organism: Leishmania donovani
Entry authors: Ghosh S, Biswas G, Datta AK, Banerjee R

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193639 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 19.11 KDa
Source organism: Leishmania donovani
Expression system: Escherichia coli M15
UniProt:
  • Canonical: Q9U9R3 (Residues: 22-187; Coverage: 100%)
Gene name: CYP
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P43212
Unit cell:
a: 48.618Å b: 48.618Å c: 141.322Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.178 0.223
Expression system: Escherichia coli M15

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