EC 2.3.1.286: Protein acetyllysine N-acetyltransferase
Reaction catalysed:
(1a) [protein]-N(6)-acetyl-L-lysine + NAD(+) = [protein]-N(6)-(1,1-(5-adenosylyl-alpha-D-ribose-1,2-di-O-yl)ethyl)-L-lysine + nicotinamide
Systematic name:
[Protein]-N(6)-acetyl-L-lysine:NAD(+) N-acetyltransferase (NAD(+)-hydrolyzing; 2''-O-acetyl-ADP-D-ribose-forming)
Alternative Name(s):
- NAD(+)-dependent protein deacetylase
- Protein lysine deacetylase
- Sir2
GO terms
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned