› 6l7j

X-ray diffraction
1.8Å resolution

Quinolone synthase (QNS) from Aegle marmelos Correa., complexed with Coenzyme A

Released:
DOI: 10.2210/pdb6l7j/pdb
PDB entry 6l7j coloured by chain, front view.
PDB entry 6l7j coloured by chain, side view.
PDB entry 6l7j coloured by chain, top view.
Source organism: Aegle marmelos
Primary publication:
Structural and mechanistic insights into Quinolone Synthase to address its functional promiscuity
Mallika V, Abhinav KV, Frandsen KEH, Soniya EV
Commun Biol (2024)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125936 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Type III polyketide synthase Chain: A
Molecule details ›
Chain: A
Length: 391 amino acids
Theoretical weight: 42.93 KDa
Source organism: Aegle marmelos
Expression system: Escherichia coli
UniProt:
  • Canonical: M1HE54 (Residues: 1-391; Coverage: 100%)
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand COA 1 x COA
2 modified residues:
Ligand CSO 1 x CSO
Ligand CSD 1 x CSD

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: R32
Unit cell:
a: 150.86Å b: 150.86Å c: 105.61Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.175 0.199
Expression system: Escherichia coli

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