› 6l98

X-ray diffraction
1.77Å resolution

Crystalline cast nephropathy-causing Bence-Jones protein AK: An entire immunoglobulin lambda light chain dimer

Released:
DOI: 10.2210/pdb6l98/pdb
PDB entry 6l98 coloured by chain, front view.
PDB entry 6l98 coloured by chain, side view.
PDB entry 6l98 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Multiple Myeloma-Associated Ig Light Chain Crystalline Cast Nephropathy.
Matsumura H, Furukawa Y, Nakagaki T, Furutani C, Osanai S, Noguchi K, Odaka M, Yohda M, Ohtani H, Michishita Y, Kawabata Y, Kitabayashi A, Ikeda S, Nara M, Komatsuda A, Takahashi N, Wakui H
Kidney Int Rep 5 1595-1602 (2020)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-214102 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bence-Jones protein lambda light chain AK Chains: A, B
Molecule details ›
Chains: A, B
Length: 213 amino acids
Theoretical weight: 22.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: P212121
Unit cell:
a: 61.379Å b: 71.794Å c: 98.455Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.229 0.265
Expression system: Homo sapiens

Quick links