6lhd

X-ray diffraction
2.5Å resolution

Crystal structure of p53/BCL-xL fusion complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-138104 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bcl-2-like protein 1; Cellular tumor antigen p53 Chains: A, B
Molecule details ›
Chains: A, B
Length: 375 amino acids
Theoretical weight: 41.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07817 (Residues: 2-201; Coverage: 69%)
  • Canonical: P04637 (Residues: 96-292; Coverage: 50%)
Gene names: BCL2L, BCL2L1, BCLX, P53, TP53
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U1
Spacegroup: P21
Unit cell:
a: 72.221Å b: 68.85Å c: 75.028Å
α: 90° β: 110.27° γ: 90°
R-values:
R R work R free
0.205 0.202 0.26
Expression system: Escherichia coli