6lit

X-ray diffraction
2Å resolution

Estrogen-related receptor beta(ERR2) in complex with BPA

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
PDBe Complex ID:
PDB-CPX-132002 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Steroid hormone receptor ERR2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 230 amino acids
Theoretical weight: 26.25 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95718 (Residues: 204-433; Coverage: 53%)
Gene names: ERRB2, ESRL2, ESRRB, NR3B2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Nuclear receptor coactivator 2 Chains: D, E
Molecule details ›
Chains: D, E
Length: 11 amino acids
Theoretical weight: 1.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15596 (Residues: 686-696; Coverage: 1%)
Gene names: BHLHE75, NCOA2, SRC2, TIF2

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P1
Unit cell:
a: 44.951Å b: 45.027Å c: 57.368Å
α: 84.31° β: 80.02° γ: 79.31°
R-values:
R R work R free
0.193 0.19 0.238
Expression system: Escherichia coli