EC 7.2.2.10: P-type Ca(2+) transporter
Reaction catalysed:
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Systematic name:
ATP phosphohydrolase (P-type, Ca(2+)-transporting)
Alternative Name(s):
- Ca(2+)-pumping ATPase
- Ca(2+)-transporting ATPase
- Calcium pump
- Calcium-translocating P-type ATPase
- Plasma membrane Ca-ATPase
- Sarco(endo)plasmic reticulum Ca(2+)-ATPase
- Sarcoplasmic reticulum ATPase
GO terms
Biochemical function:
- lncRNA binding
- P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential
- metal ion binding
- S100 protein binding
- transmembrane transporter binding
- enzyme binding
- ATP hydrolysis activity
- ATP binding
- protein binding
- calcium ion binding
- P-type calcium transporter activity
- transporter activity
- nucleotide binding
Biological process:
- mitochondrion-endoplasmic reticulum membrane tethering
- calcium ion import into sarcoplasmic reticulum
- regulation of cardiac conduction
- calcium ion transport from cytosol to endoplasmic reticulum
- regulation of calcium ion-dependent exocytosis of neurotransmitter
- negative regulation of receptor binding
- organelle localization by membrane tethering
- regulation of cardiac muscle cell action potential involved in regulation of contraction
- regulation of cardiac muscle cell membrane potential
- calcium ion transmembrane transport
- sarcoplasmic reticulum calcium ion transport
- neuron cellular homeostasis
- negative regulation of heart contraction
- response to endoplasmic reticulum stress
- cellular response to oxidative stress
- monoatomic ion transmembrane transport
- T-tubule organization
- positive regulation of endoplasmic reticulum calcium ion concentration
- endoplasmic reticulum calcium ion homeostasis
- autophagosome membrane docking
- cardiac muscle hypertrophy in response to stress
- transition between fast and slow fiber
- regulation of cardiac muscle contraction by calcium ion signaling
- positive regulation of cardiac muscle cell apoptotic process
- positive regulation of heart rate
- epidermis development
- cell adhesion
- organelle organization
- ER-nucleus signaling pathway
- intracellular calcium ion homeostasis
- calcium ion transport
- regulation of the force of heart contraction
- autophagosome assembly
Protein families (Pfam)
InterPro annotations