› 6ltq

X-ray diffraction
1.85Å resolution

Crystal structure of pyrrolidone carboxyl peptidase from thermophilic keratin degrading bacterium Fervidobacterium islandicum AW-1 (FiPcp)

Released:
DOI: 10.2210/pdb6ltq/pdb
PDB entry 6ltq coloured by chain, front view.
PDB entry 6ltq coloured by chain, side view.
PDB entry 6ltq coloured by chain, top view.
Source organism: Fervidobacterium islandicum
Primary publication:
Structure of oxidized pyrrolidone carboxypeptidase from Fervidobacterium islandicum AW-1 reveals unique structural features for thermostability and keratinolysis.
Dhanasingh I, Sung JY, La JW, Kang E, Lee DW, Lee SH
Biochem Biophys Res Commun 540 101-107 (2021)
PMID: 33460839

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-244839 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyroglutamyl-peptidase I Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 221 amino acids
Theoretical weight: 24.81 KDa
Source organism: Fervidobacterium islandicum
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand GOL 18 x GOL
Ligand 1PE 1 x 1PE
1 modified residue:
Ligand OCS 4 x OCS

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P21
Unit cell:
a: 61.035Å b: 86.61Å c: 93.529Å
α: 90° β: 105.18° γ: 90°
R-values:
R R work R free
0.176 0.174 0.224
Expression system: Escherichia coli

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