Function and Biology Details
Reactions catalysed:
ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate
Guanosine 3',5'-bis(diphosphate) + H(2)O = guanosine 5'-diphosphate + diphosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Bifunctional (p)ppGpp synthase/hydrolase RelA (preferred)
PDBe Complex ID:
PDB-CPX-161550 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bifunctional (p)ppGpp synthase/hydrolase RelA
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 10.08 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
Sequence domains: ACT domain
Length: 90 amino acids
Theoretical weight: 10.08 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
- Canonical:
P9WHG9 (Residues: 660-738; Coverage: 11%)
Sequence domains: ACT domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
36%
Refinement method:
simulated annealing
Expression system: Escherichia coli
