› 6lzp

Solution NMR

The solution structure of N-terminal elongated hSNF5 RPT1 domain

Released:
DOI: 10.2210/pdb6lzp/pdb
PDB entry 6lzp coloured by chain, ensemble of 20 models, front view.
PDB entry 6lzp coloured by chain, ensemble of 20 models, side view.
PDB entry 6lzp coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction.
Han J, Kim I, Park JH, Yun JH, Joo K, Kim T, Park GY, Ryu KS, Ko YJ, Mizutani K, Park SY, Seong RH, Lee J, Suh JY, Lee W
OpenAccess logo Int J Mol Sci 21 (2020)
PMID: 32244797

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171401 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 10.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q12824 (Residues: 171-258; Coverage: 23%)
Gene names: BAF47, INI1, SMARCB1, SNF5L1
Sequence domains: SNF5 / SMARCB1 / INI1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

Immunotherapy for SMARCB1-Deficient Sarcomas: Current Evidence and Future Developments.
Ngo et al. (2022)
2 other articles