Function and Biology

Crystal Structure Determination of Human/Porcine Chimera Coagulation Factor VIII

Source organisms:
Biochemical function: oxidoreductase activity
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00754
Domain description: F5/8 type C domain
Occurring in:
  1. Coagulation factor VIII
The deposited structure of PDB entry 6mf0 contains 4 copies of Pfam domain PF00754 (F5/8 type C domain) in Coagulation factor VIII. Showing 2 copies in chain A.

PF07732
Domain description: Multicopper oxidase
Occurring in:
  1. Coagulation factor VIII
The deposited structure of PDB entry 6mf0 contains 4 copies of Pfam domain PF07732 (Multicopper oxidase) in Coagulation factor VIII. Showing 2 copies in chain A.

PF07731
Domain description: Multicopper oxidase
Occurring in:
  1. Coagulation factor VIII
The deposited structure of PDB entry 6mf0 contains 2 copies of Pfam domain PF07731 (Multicopper oxidase) in Coagulation factor VIII. Showing 1 copy in chain A.

PF00394
Domain description: Multicopper oxidase
Occurring in:
  1. Coagulation factor VIII
The deposited structure of PDB entry 6mf0 contains 2 copies of Pfam domain PF00394 (Multicopper oxidase) in Coagulation factor VIII. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000421
Domain description: Coagulation factor 5/8, C-terminal domain
Occurring in:
  1. Coagulation factor VIII
IPR008972
Domain description: Cupredoxin
Occurring in:
  1. Coagulation factor VIII
IPR008979
Domain description: Galactose-binding-like domain superfamily
Occurring in:
  1. Coagulation factor VIII
IPR033138
Domain description: Multicopper oxidases, conserved site
Occurring in:
  1. Coagulation factor VIII
IPR011707
Domain description: Multicopper oxidase-like, N-terminal
Occurring in:
  1. Coagulation factor VIII
IPR024715
Domain description: Coagulation factor 5/8-like
Occurring in:
  1. Coagulation factor VIII
IPR011706
Domain description: Multicopper oxidase, C-terminal
Occurring in:
  1. Coagulation factor VIII
IPR001117
Domain description: Multicopper oxidase, second cupredoxin domain
Occurring in:
  1. Coagulation factor VIII