EC 3.4.25.1: Proteasome endopeptidase complex
Reaction catalysed:
Cleavage of peptide bonds with very broad specificity.
Alternative Name(s):
- 26S protease
- Alkaline protease
- Ingensin
- Large multicatalytic protease
- Lens neutral proteinase
- MCP
- Macropain
- Multicatalytic endopeptidase complex
- Multicatalytic proteinase
- Multicatalytic proteinase (complex)
- Prosome
- Proteasome
- Proteasome organelle
- Tricorn protease
- Tricorn proteinase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
PF00227
Domain description:
Proteasome subunit
Occurring in:
Occurring in:
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit beta type-6, putative
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
PF10584
Domain description:
Proteasome subunit A N-terminal signature
Occurring in:
Occurring in:
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
InterPro annotations
IPR029055
Domain description:
Nucleophile aminohydrolases, N-terminal
Occurring in:
Occurring in:
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit beta type-6, putative
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- 20S proteasome beta-6 subunit
- Proteasome subunit beta
IPR001353
Domain description:
Proteasome, subunit alpha/beta
Occurring in:
Occurring in:
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit beta type-6, putative
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- Proteasome subunit beta
- 20S proteasome beta-6 subunit
- Proteasome subunit beta
IPR000426
Domain description:
Proteasome alpha-subunit, N-terminal domain
Occurring in:
Occurring in:
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome subunit alpha type
- Proteasome alpha-type subunits domain-containing protein
- Proteasome alpha-type subunits domain-containing protein
IPR036997
Domain description:
Proteasome activator PA28, C-terminal domain superfamily
Occurring in:
Occurring in: