› 6n1m

X-ray diffraction
1.55Å resolution

Crystal structure of Fumarate hydratase class II from Legionella pneumophila Philadelphia 1

Released:
DOI: 10.2210/pdb6n1m/pdb
PDB entry 6n1m coloured by chain, front view.
PDB entry 6n1m coloured by chain, side view.
PDB entry 6n1m coloured by chain, top view.
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
(S)-malate = fumarate + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178563 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fumarate hydratase class II Chain: A
Molecule details ›
Chain: A
Length: 472 amino acids
Theoretical weight: 51.45 KDa
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5ZRE5 (Residues: 1-464; Coverage: 100%)
Gene names: fum, fumC, lpg2937
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand SO4 2 x SO4
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: I222
Unit cell:
a: 58.23Å b: 122.08Å c: 128.69Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.144 0.143 0.165
Expression system: Escherichia coli BL21(DE3)

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