› 6nix

X-ray diffraction
2.1Å resolution

Crystal structure of Immune Receptor

Released:
DOI: 10.2210/pdb6nix/pdb
PDB entry 6nix coloured by chain, front view.
PDB entry 6nix coloured by chain, side view.
PDB entry 6nix coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Ting YT, Reid HH, Rossjohn J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135306 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class II histocompatibility antigen, DR alpha chain Chain: A
Molecule details ›
Chain: A
Length: 189 amino acids
Theoretical weight: 21.92 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01903 (Residues: 30-206; Coverage: 77%)
Gene names: HLA-DRA, HLA-DRA1
Sequence domains:
HLA class II histocompatibility antigen, DRB1 beta chain Chain: B
Molecule details ›
Chain: B
Length: 200 amino acids
Theoretical weight: 23.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01911 (Residues: 30-219; Coverage: 80%)
Gene name: HLA-DRB1
Sequence domains:
Collagen alpha-1(II) chain Chain: C
Molecule details ›
Chain: C
Length: 15 amino acids
Theoretical weight: 1.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P02458 (Residues: 459-473; Coverage: 1%)
Gene name: COL2A1

Ligands and Environments

2 bound ligands:
Ligand NAG 3 x NAG
Ligand B3P 1 x B3P
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: C2221
Unit cell:
a: 67.92Å b: 178.038Å c: 76.239Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.178 0.235
Expression systems:
  • Homo sapiens
  • Not provided

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