› 6nu0

Solution NMR

Solution NMR structure of 1918 NS1 effector domain

Released:
DOI: 10.2210/pdb6nu0/pdb
PDB entry 6nu0 coloured by chain, ensemble of 20 models, front view.
PDB entry 6nu0 coloured by chain, ensemble of 20 models, side view.
PDB entry 6nu0 coloured by chain, ensemble of 20 models, top view.
Source organism: Influenza A virus
Primary publication:
The structure and conformational plasticity of the nonstructural protein 1 of the 1918 influenza A virus.
Shen Q, Cho JH
Biochem Biophys Res Commun 518 178-182 (2019)
PMID: 31420169

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189303 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 1 Chain: A
Molecule details ›
Chain: A
Length: 230 amino acids
Theoretical weight: 26.07 KDa
Source organism: Influenza A virus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99AU3 (Residues: 1-230; Coverage: 100%)
Gene name: NS
Sequence domains: Influenza non-structural protein (NS1)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The Central Role of Non-Structural Protein 1 (NS1) in Influenza Biology and Infection.
Rosário-Ferreira et al. (2020)
1 more

2 mentions without citation

Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses.
Cho et al. (2020)
1 more