› 6nyn

Electron Microscopy
3.5Å resolution

Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2e (OA-2e)

Released:
DOI: 10.2210/pdb6nyn/pdb
PDB entry 6nyn coloured by chain, front view.
PDB entry 6nyn coloured by chain, side view.
PDB entry 6nyn coloured by chain, top view.
Source organism: Helicobacter pylori
Primary publication:
Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Zhang K, Zhang H, Li S, Pintilie GD, Mou TC, Gao Y, Zhang Q, van den Bedem H, Schmid MF, Au SWN, Chiu W
OpenAccess logo Proc Natl Acad Sci U S A 116 6800-6805 (2019)
PMID: 30894496
Related structures: EMD-0547

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175338 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vacuolating cytotoxin autotransporter Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 821 amino acids
Theoretical weight: 88.46 KDa
Source organism: Helicobacter pylori
UniProt:
  • Canonical: Q48245 (Residues: 34-854; Coverage: 66%)
Gene name: vacA
Sequence domains: Vacuolating cyotoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-0547

Quick links

Citations

3 review citations

Cryo-electron tomography related radiation-damage parameters for individual-molecule 3D structure determination.
Xue et al. (2022)
2 more

1 mention without citation

Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution.
Zhang et al. (2019)