Function and Biology Details
Reaction catalysed:
ATP + H(2)O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Cystic fibrosis transmembrane conductance regulator
- ABC transporter-like, ATP-binding domain
- P-loop containing nucleoside triphosphate hydrolase
- ABC transporter type 1, transmembrane domain
- ABC transporter type 1, transmembrane domain superfamily
- AAA+ ATPase domain
- CFTR regulator domain
- ABC transporter-like, conserved site
1 more domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146645 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cystic fibrosis transmembrane conductance regulator
Molecule details ›
Chain: A
Length: 1489 amino acids
Theoretical weight: 169.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 1489 amino acids
Theoretical weight: 169.35 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P13569 (Residues: 1-1480; Coverage: 100%)
Sequence domains:
