Function and Biology

Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41) and phosphatidic acid (06:0 PA)

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. PGZL1 heavy chain
  2. PGZL1 light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. PGZL1 heavy chain
  2. PGZL1 light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. PGZL1 heavy chain
  2. PGZL1 light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. PGZL1 heavy chain
  2. PGZL1 light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. PGZL1 heavy chain
  2. PGZL1 light chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. PGZL1 heavy chain
  2. PGZL1 light chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. PGZL1 heavy chain
  2. PGZL1 light chain