› 6oat

X-ray diffraction
3.17Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103186 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
RNA-dependent RNA polymerase Chains: A, C
Molecule details ›
Chains: A, C
Length: 178 amino acids
Theoretical weight: 20.05 KDa
Source organism: Ganjam virus
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A191KWA2 (Residues: 1-169; Coverage: 4%)
Sequence domains: OTU-like cysteine protease
Interferon stimulated gene 17 Chains: B, D
Molecule details ›
Chains: B, D
Length: 156 amino acids
Theoretical weight: 17.45 KDa
Source organism: Ovis aries
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:
Ligand AYE 2 x AYE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 18-ID
Spacegroup: P61
Unit cell:
a: 55.388Å b: 55.388Å c: 497.31Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.256 0.251 0.304
Expression system: Escherichia coli

Quick links

Citations

3 review citations

How ISG15 combats viral infection.
Freitas et al. (2020)
2 more

2 mentions without citation

Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
Dzimianski et al. (2019)
1 more