6ocp

X-ray diffraction
2.35Å resolution

Crystal structure of a human GABAB receptor peptide bound to KCTD16 T1

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero octadecamer (preferred)
PDBe Complex ID:
PDB-CPX-131165 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
BTB/POZ domain-containing protein KCTD16 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O
Length: 113 amino acids
Theoretical weight: 13.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q68DU8 (Residues: 22-134; Coverage: 26%)
Gene names: KCTD16, KIAA1317
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A
Gamma-aminobutyric acid type B receptor subunit 2 Chains: P, Q, R
Molecule details ›
Chains: P, Q, R
Length: 15 amino acids
Theoretical weight: 1.62 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O75899 (Residues: 895-909; Coverage: 2%)
Gene names: GABBR2, GPR51, GPRC3B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P1
Unit cell:
a: 56.792Å b: 69.105Å c: 137.889Å
α: 102.19° β: 94.83° γ: 91.15°
R-values:
R R work R free
0.222 0.222 0.241
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided