Structure analysis

Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C16-crypto Acyl Carrier Protein, AcpP

X-ray diffraction
2.5Å resolution
Source organism: Escherichia coli K-12
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 31475.59 Å2
Buried surface area: 8449.1 Å2
Dissociation area: 1,321.82 Å2
Dissociation energy (ΔGdiss): -8.9 kcal/mol
Dissociation entropy (TΔSdiss): 22.74 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-141281

Macromolecules

Chains: A, B
Length: 406 amino acids
Theoretical weight: 42.66 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0A953 (Residues: 1-406; Coverage: 100%)
Gene names: JW2320, b2323, fabB, fabC
Pfam:
InterPro:

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Chains: C, D
Length: 78 amino acids
Theoretical weight: 8.65 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0A6A8 (Residues: 1-78; Coverage: 100%)
Gene names: JW1080, acpP, b1094
Pfam: Phosphopantetheine attachment site
InterPro:

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