Function and Biology

Human OX40R (TNFRSF4) bound to Fab 3C8

Source organism: Homo sapiens
Biochemical function: tumor necrosis factor receptor activity
Biological process: inflammatory response
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00020
Domain description: TNFR/NGFR cysteine-rich region
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 4
The deposited structure of PDB entry 6okm contains 2 copies of Pfam domain PF00020 (TNFR/NGFR cysteine-rich region) in Tumor necrosis factor receptor superfamily member 4. Showing 2 copies in chain C [auth R].

InterPro InterPro annotations
IPR001368
Domain description: TNFR/NGFR cysteine-rich region
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 4
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. Fab 3C8 Heavy Chain
  2. Fab 3C8 light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Fab 3C8 Heavy Chain
  2. Fab 3C8 light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Fab 3C8 Heavy Chain
  2. Fab 3C8 light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Fab 3C8 Heavy Chain
  2. Fab 3C8 light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Fab 3C8 Heavy Chain
  2. Fab 3C8 light chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. Fab 3C8 Heavy Chain
  2. Fab 3C8 light chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Fab 3C8 Heavy Chain
  2. Fab 3C8 light chain
IPR034022
Domain description: Tumour necrosis factor receptor 4, N-terminal
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 4
IPR020445
Domain description: Tumour necrosis factor receptor 4
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 4
IPR038052
Domain description: Chaperonin-like RbcX superfamily
Occurring in:
  1. Tumor necrosis factor receptor superfamily member 4