› 6or5

Electron Microscopy
4Å resolution

Full-length S. pombe Mdn1 in the presence of AMPPNP (ring region)

Released:
DOI: 10.2210/pdb6or5/pdb
PDB entry 6or5 coloured by chain, front view.
PDB entry 6or5 coloured by chain, side view.
PDB entry 6or5 coloured by chain, top view.
Source organism: Schizosaccharomyces pombe
Primary publication:
Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis.
Chen Z, Suzuki H, Kobayashi Y, Wang AC, DiMaio F, Kawashima SA, Walz T, Kapoor TM
Cell 175 822-834.e18 (2018)
PMID: 30318141
Related structures: EMD-9032

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131703 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Midasin Chain: A
Molecule details ›
Chain: A
Length: 4717 amino acids
Theoretical weight: 538.38 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Trichoplusia ni
UniProt:
  • Canonical: O94248 (Residues: 1-4717; Coverage: 100%)
Gene names: SPCC737.08, mdn1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ANP 5 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4Å
Relevant EMDB volumes: EMD-9032
Expression system: Trichoplusia ni

Quick links

Citations

8 review citations

Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis.
Prattes et al. (2019)
7 more

1 mention without citation

Long-range intramolecular allostery and regulation in the dynein-like AAA protein Mdn1.
Mickolajczyk et al. (2020)