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Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor, TM + cytosolic helix construct

Source organism: Influenza A virus (A/Memphis/1/1971(H3N2))
Biochemical function: proton transmembrane transporter activity
Biological process: proton transmembrane transport
Cellular component: virion membrane

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF00599
Domain description: Influenza Matrix protein (M2)
Occurring in:
  1. Matrix protein 2
The deposited structure of PDB entry 6oug contains 8 copies of Pfam domain PF00599 (Influenza Matrix protein (M2)) in Matrix protein 2. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR002089
Domain description: Influenza virus matrix protein 2
Occurring in:
  1. Matrix protein 2

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