EC 3.4.23.16: HIV-1 retropepsin
Reaction catalysed:
Specific for a P1 residue that is hydrophobic, and P1' variable, but often Pro.
Alternative Name(s):
- Gag protease
- HIV aspartyl protease
- HIV proteinase
- HIV-1 protease
- HIV-2 protease
- Human immunodeficiency virus type 1 protease
- Retroproteinase
EC 3.1.26.13: Retroviral ribonuclease H
Reaction catalysed:
Endohydrolysis of RNA in RNA/DNA hybrids. Three different cleavage modes: 1. sequence-specific internal cleavage of RNA. Human immunodeficiency virus type 1 and Moloney murine leukemia virus enzymes prefer to cleave the RNA strand one nucleotide away from the RNA-DNA junction. 2. RNA 5'-end directed cleavage 13-19 nucleotides from the RNA end. 3. DNA 3'-end directed cleavage 15-20 nucleotides away from the primer terminus.
Systematic name:
-
Alternative Name(s):
- HIV RNase H
- RT/RNase H
- Retroviral reverse transcriptase RNaseH
EC 3.1.13.2: Exoribonuclease H
Reaction catalysed:
3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid
Systematic name:
-
EC 2.7.7.7: DNA-directed DNA polymerase
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Systematic name:
Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)
Alternative Name(s):
- DNA duplicase
- DNA nucleotidyltransferase
- DNA nucleotidyltransferase (DNA-directed)
- DNA polymerase
- DNA polymerase I
- DNA polymerase II
- DNA polymerase III
- DNA polymerase alpha
- DNA polymerase beta
- DNA polymerase gamma
- DNA replicase
- DNA-dependent DNA polymerase
- Deoxynucleate polymerase
- Deoxyribonucleate nucleotidyltransferase
- Deoxyribonucleic acid duplicase
- Deoxyribonucleic acid polymerase
- Deoxyribonucleic duplicase
- Deoxyribonucleic polymerase
- Deoxyribonucleic polymerase I
- Duplicase
- Klenow fragment
- Sequenase
- Taq DNA polymerase
- Taq Pol I
- Tca DNA polymerase
EC 2.7.7.49: RNA-directed DNA polymerase
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Systematic name:
Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed)
Alternative Name(s):
- DNA nucleotidyltransferase (RNA-directed)
- RNA revertase
- RNA-dependent DNA polymerase
- RNA-dependent deoxyribonucleate nucleotidyltransferase
- RNA-instructed DNA polymerase
- RT
- Reverse transcriptase
- Revertase
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Protein family (Pfam)![The deposited structure of PDB entry 6oxt contains 2 copies of Pfam domain PF00077 (Retroviral aspartyl protease) in Protease. Showing 1 copy in chain B [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/6oxt_1_A_Pfam_PF00077_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>6oxt</span> contains 2 copies of Pfam domain <span class='highlight'>PF00077 (Retroviral aspartyl protease)</span> in <span class='highlight'>Protease</span>. Showing 1 copy in chain <span class='highlight'>B [auth A]</span>.")
InterPro annotations