6p8d

X-ray diffraction
2.1Å resolution

Vaccine-elicited murine FP-targeting antibody vFP6.01 in complex with HIV fusion peptide (residue 512-519)

Released:
Entry authors: Xu K, Liu K, Wang Y, Kwong PD

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-209079 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Antibody VFP6.01 heavy chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 218 amino acids
Theoretical weight: 23.58 KDa
Source organism: Mus musculus
Antibody VFP6.01 light chain Chains: B, E
Molecule details ›
Chains: B, E
Length: 219 amino acids
Theoretical weight: 24.3 KDa
Source organism: Mus musculus
Transmembrane protein gp41 Chains: C, F
Molecule details ›
Chains: C, F
Length: 8 amino acids
Theoretical weight: 733 Da
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 512-519; Coverage: 1%)
Gene name: env

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 42.311Å b: 119.777Å c: 185.503Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.272 0.27 0.309
Expression system: Not provided