6pci

Electron Microscopy
4.12Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero octadecamer (preferred)
PDBe Complex ID:
PDB-CPX-207218 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (7 distinct):
Filoviruses glycoprotein extracellular domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 278 amino acids
Theoretical weight: 31.1 KDa
Source organism: Ebola virus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A068J419 (Residues: 32-309; Coverage: 41%)
Gene name: GP
Sequence domains: Filovirus glycoprotein
rEBOV-548 Fab heavy chain Chains: H, I, J
Molecule details ›
Chains: H, I, J
Length: 234 amino acids
Theoretical weight: 25.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
rEBOV-548 Fab light chain Chains: K, L, M
Molecule details ›
Chains: K, L, M
Length: 214 amino acids
Theoretical weight: 23.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Filoviruses glycoprotein extracellular domain-containing protein Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 203 amino acids
Theoretical weight: 22.14 KDa
Source organism: Zaire ebolavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A068J419 (Residues: 461-633, 634-636, 637-651; Coverage: 28%)
Gene name: GP
Sequence domains: Envelope glycoprotein GP2-like, HR1-HR2
rEBOV-520 Fab light chain Chains: Q, R, S
Molecule details ›
Chains: Q, R, S
Length: 215 amino acids
Theoretical weight: 23.43 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
rEBOV-520 Fab heavy chain Chains: N, O, P
Molecule details ›
Chains: N, O, P
Length: 227 amino acids
Theoretical weight: 24.07 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.12Å
Relevant EMDB volumes: EMD-20301
Expression system: Homo sapiens