› 6pds

X-ray diffraction
1.89Å resolution

Vaccine-elicited NHP FP-targeting antibody 0PV-a.04 in complex with HIV fusion peptide (residue 512-519)

Released:
DOI: 10.2210/pdb6pds/pdb
PDB entry 6pds coloured by chain, front view.
PDB entry 6pds coloured by chain, side view.
PDB entry 6pds coloured by chain, top view.
Source organisms:
Entry authors: Xu K, Liu K, Wang Y, Kwong PD

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209081 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
antibody 0PV-a.04 light chain Chains: A, L
Molecule details ›
Chains: A, L
Length: 212 amino acids
Theoretical weight: 23.06 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
antibody 0PV-a.04 heavy chain Chains: B, H
Molecule details ›
Chains: B, H
Length: 220 amino acids
Theoretical weight: 23.82 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
Transmembrane protein gp41 Chains: C, G
Molecule details ›
Chains: C, G
Length: 8 amino acids
Theoretical weight: 733 Da
Source organism: Human immunodeficiency virus 1
Expression system: Not provided
UniProt:
  • Canonical: P04578 (Residues: 512-519; Coverage: 1%)
Gene name: env

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 69.857Å b: 74.381Å c: 187.198Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.193 0.22
Expression systems:
  • Homo sapiens
  • Not provided

Quick links