› 6php

X-ray diffraction
1.65Å resolution

Crystal structure of glucagon analog with 4-bromo-phenylalanine substitutions at position 6 and 22 in space group I41 at 1.65 A resolution

Released:
DOI: 10.2210/pdb6php/pdb
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PDB entry 6php coloured by chain, front view.
PDB entry 6php coloured by chain, side view.
PDB entry 6php coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Mroz PA, Gonzalez-Gutierrez G, DiMarchi RD

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134154 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucagon Chain: A
Molecule details ›
Chain: A
Length: 29 amino acids
Theoretical weight: 3.64 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01275 (Residues: 53-81; Coverage: 18%)
Gene name: GCG
Sequence domains: Peptide hormone

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: I41
Unit cell:
a: 41.712Å b: 41.712Å c: 30.434Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.225 0.246
Expression system: Not provided

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