6pog

X-ray diffraction
2.76Å resolution

Crystal structure of the NELL2 EGF1-6-Robo3 FN1 complex

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-188633 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Roundabout homolog 3 Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 12.15 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q96MS0 (Residues: 551-663; Coverage: 8%)
Gene name: ROBO3
Sequence domains: Fibronectin type III domain
Protein kinase C-binding protein NELL2 Chain: B
Molecule details ›
Chain: B
Length: 249 amino acids
Theoretical weight: 27.49 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q99435 (Residues: 397-638; Coverage: 30%)
Gene names: NELL2, NRP2
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 41.873Å b: 90.439Å c: 171.576Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.239 0.237 0.264
Expression system: Trichoplusia ni