Function and Biology Details
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Herpesvirus major capsid protein
- Gammaherpesvirus capsid
- Herpesvirus capsid protein 2
- Herpesvirus major capsid protein, upper domain superfamily
- Herpesvirus large tegument protein, USP domain
- Herpesvirus UL25
- Herpesvirus capsid shell protein 1
- Papain-like cysteine peptidase superfamily
2 more domains
Structure analysis Details
Assembly composition:
hetero 21-mer (preferred)
PDBe Complex ID:
PDB-CPX-111690 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (7 distinct):
Capsid vertex component 1
Molecule details ›
Chain: k
Length: 454 amino acids
Theoretical weight: 49.59 KDa
Source organism: Human herpesvirus 8 strain GK18
UniProt:
Sequence domains: Herpesvirus UL17 protein
Length: 454 amino acids
Theoretical weight: 49.59 KDa
Source organism: Human herpesvirus 8 strain GK18
UniProt:
- Canonical:
F5HB39 (Residues: 1-454; Coverage: 100%)
Sequence domains: Herpesvirus UL17 protein
Capsid vertex component 2
Molecule details ›
Chains: l, m
Length: 549 amino acids
Theoretical weight: 61.49 KDa
Source organism: Human herpesvirus 8 strain GK18
UniProt:
Sequence domains: Herpesvirus UL25 family
Length: 549 amino acids
Theoretical weight: 61.49 KDa
Source organism: Human herpesvirus 8 strain GK18
UniProt:
- Canonical: Q2HRB3 (Residues: 1-549; Coverage: 100%)
Sequence domains: Herpesvirus UL25 family
Large tegument protein deneddylase
Triplex capsid protein 1
Putative minor capsid protein
Major capsid protein
Small capsomere-interacting protein
