6pv6

Electron Microscopy
4.5Å resolution

Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots

Released:

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-159289 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ryanodine receptor 1 Chains: B, E, G, I
Molecule details ›
Chains: B, E, G, I
Length: 4687 amino acids
Theoretical weight: 502.25 KDa
Source organism: Oryctolagus cuniculus
Peptidyl-prolyl cis-trans isomerase FKBP1B Chains: A, F, H, J
Molecule details ›
Chains: A, F, H, J
Length: 108 amino acids
Theoretical weight: 11.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P68106 (Residues: 1-108; Coverage: 100%)
Gene names: FKBP12.6, FKBP1B, FKBP1L, FKBP9, OTK4
Sequence domains: FKBP-type peptidyl-prolyl cis-trans isomerase

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-20486
Expression system: Escherichia coli