6pv7

Electron Microscopy
3.34Å resolution

Human alpha3beta4 nicotinic acetylcholine receptor in complex with nicotine

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-211022 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (7 distinct):
Neuronal acetylcholine receptor subunit alpha-3 Chains: A, D
Molecule details ›
Chains: A, D
Length: 525 amino acids
Theoretical weight: 60.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Neuronal acetylcholine receptor subunit beta-4 Chains: B, C, E
Molecule details ›
Chains: B, C, E
Length: 538 amino acids
Theoretical weight: 61.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
IgG2b Fab heavy chain Chains: F, H
Kappa Fab light chain Chains: G, I

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 3.34Å
Relevant EMDB volumes: EMD-20487
Expression system: Homo sapiens