› 6pvt

Solid-state NMR

Influenza B M2 Proton Channel in the Open State - SSNMR Structure at pH 4.5

Released:
DOI: 10.2210/pdb6pvt/pdb
PDB entry 6pvt coloured by chain, ensemble of 10 models, front view.
PDB entry 6pvt coloured by chain, ensemble of 10 models, side view.
PDB entry 6pvt coloured by chain, ensemble of 10 models, top view.
Source organism: Influenza B virus (B/Maryland/1/2001)
Primary publication:
Atomic structures of closed and open influenza B M2 proton channel reveal the conduction mechanism.
Mandala VS, Loftis AR, Shcherbakov AA, Pentelute BL, Hong M
OpenAccess logo Nat Struct Mol Biol 27 160-167 (2020)
PMID: 32015551

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167271 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BM2 protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 51 amino acids
Theoretical weight: 5.95 KDa
Source organism: Influenza B virus (B/Maryland/1/2001)
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 10%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

11 review citations

Characterization of the SARS-CoV-2 E Protein: Sequence, Structure, Viroporin, and Inhibitors.
Cao et al. (2021)
10 more

5 mentions without citation

Solid-State NMR for Studying the Structure and Dynamics of Viral Assemblies.
Lecoq et al. (2020)
4 more