› 6pyd

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-232249 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
3E9 anti-marinobufagenin antibody Fab heavy chain, recloned with human IgG4 C region Chains: A, H
Molecule details ›
Chains: A, H
Length: 222 amino acids
Theoretical weight: 24.19 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus
3E9 antibody Fab light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 219 amino acids
Theoretical weight: 24.08 KDa
Source organism: Mus musculus
Expression system: Cricetulus griseus

Ligands and Environments

1 bound ligand:
Ligand P4S 2 x P4S
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P1
Unit cell:
a: 49.92Å b: 67.69Å c: 71.986Å
α: 97.37° β: 106.35° γ: 107°
R-values:
R R work R free
0.231 0.229 0.276
Expression system: Cricetulus griseus

Quick links

Citations

1 citations in other articles

Development of vaccines and antivirals for combating viral pandemics.
Pardi et al. (2020)

1 mention without citation

Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Macdonald et al. (2020)